Dangers of Smoking Around with a Portable Oxygen Machine If you smoke, smoke outside. Even if the oxygen is turned off, it isn't safe to smoke near an oxygen tank. U.S. Fire Administration Facebook If you or a loved one uses an oxygen tank at home, remember these safety tips from our Fire Marshal's Office: Never smoke in a home where oxygen is being used. ( Vaping Safety, Smoking, Dangers, Pros, Cons, Debate, E cigarettes, & Tobacco Britannica Can I Travel With My Vape Pen? Expert Flying Tips